Effect of beta adrenoceptor antagonists on baroreceptor reflex sensitivity in hypertension
نویسندگان
چکیده
منابع مشابه
Alpha- and beta-adrenoceptor antagonists.
Antagonists acting on the betaor alphaadrenoceptors are used widely in medicine and in anaesthesia. The major indications for betaadrenoceptor blockade are coronary artery disease and arterial hypertension, while those for alphaadrenoceptor blockade include arterial hypertension, paroxysmal hypertension and chronic cardiac failure. The adrenoceptor antagonists interfere with important regulator...
متن کاملCentrally infused bradykinin increases baroreceptor reflex sensitivity.
Kinins are present in the central nervous system, and central administration of bradykinin increases blood pressure and heart rate. In this study, we determined the effect of intracerebroventricular infusion of bradykinin on the baroreceptor reflex of conscious rats. Male Wistar rats were anesthetized with thiobarbital (40 mg/kg i.p.), and chronic intracerebroventricular cannulas (25 gauge) wer...
متن کاملAngiotensin-(1-7) and bradykinin in baroreceptor reflex sensitivity in hypertension.
Angiotensin-(1-7) and Bradykinin in Baroreceptor Reflex Sensitivity in Hypertension To the Editor: We read with great interest the article by Dr Nautiyal et al dealing with the relationship between angiotensin (Ang)-(1-7) and vagal function in hypertension. The results of their study demonstrated that intracerebroventricular administration of Ang-(1-7) enhanced vagal components of the barorecep...
متن کاملResponse to Angiotensin-(1-7) and Bradykinin in Baroreceptor Reflex Sensitivity in Hypertension.
Response to Angiotensin-(1-7) and Bradykinin in Barorecep tor Reflex Sensitivity in Hypertension The letter by Tsuda raises the question of whether bradykinin contributes to the effects of chronic intracerebroventricular angiotensin (Ang)-(1-7) to enhance baroreflex function in hypertensive (mRen2)27 rats. Our studies exclusively focused on the effects of Ang-(1-7) on NADPH oxidase and mitogen-...
متن کاملAssessment of baroreceptor reflex sensitivity by means of spectral analysis.
A method of determining baroreceptor reflex sensitivity is proposed that is based on spectral analysis of systolic pressure values and RR interval times, namely, the modulus (or gain) in the mid frequency band (0.07-0.14 Hz) between these two signals. Results using this method were highly correlated (0.94; n = 8) with results of the phenylephrine method. In addition, compared with the values fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 1977
ISSN: 0009-9236
DOI: 10.1002/cpt1977223293